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普立肽Plitidepsin(Aplidin)

名称 普立肽Aplidin(Plitidepsin)
CAS No. 137219-37-5
规格 mg/g/kg
纯度 ≥98%
贮存 -20°C
分子量 1110.357
序列结构 (2S)-N-[(2R)-1-[[(3S,6S,8S,12S,13R,16S,17R,20S,23S)-13-[(2S)-butan-2-yl]-12-hydroxy-20-[(4-methoxyphenyl)methyl]-6,17,21-trimethyl-3-(2-methylpropyl)-2,5,7,10,15,19,22-heptaoxo-8-propan-2-yl-9,18-dioxa-1,4,14,21-tetrazabicyclo[21.3.0]hexacosan-16-yl]amino
产品简述

Plitidepsin(又称去氢代代宁B)是从白色念珠菌海鞘中提取的一种化合物。目前正在进行临床试验测试。它是被称为去甲肾上腺素具有抗肿瘤、抗病毒和免疫抑制活性。它在缩小胰腺癌、胃癌、膀胱癌和前列腺癌的肿瘤方面显示出良好的前景。

Plitidepsin (also known as dehydrodidemnin B) is a chemical compound extracted from the ascidian Aplidium albicans. It is currently undergoing clinical trial testing. It is a member of the class of compounds known as didemnins.plitidepsin exhibits antitumor, antiviral and immunosuppressive activities. It shows promise in shrinking tumors in pancreatic, stomach, bladder, and prostate cancers.

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